Patient characteristics and expression of vascular endothelial growth factor (VEGF)
| VEGF percentage | VEGF final score | ||||||
|---|---|---|---|---|---|---|---|
| Variable | n | Median | IQR | p Value | Median | IQR | p Value |
| Two indices of VEGF are presented: percentage area stained and final score. | |||||||
| p Values were calculated by the Mann-Whitney U test or the Kruskal-Wallis test. | |||||||
| Outcome refers to the outcome five years after tumour resection. | |||||||
| Adeno, adenocarcinoma; IQR, interquartile range; SCC, squamous cell carcinoma. | |||||||
| All patients | 81 | 65.0 | 27.5 | – | 130.0 | 70.0 | – |
| Age | |||||||
| <Median | 40 | 60.0 | 23.8 | 0.404 | 122.5 | 78.8 | 0.744 |
| ≥Median | 41 | 70.0 | 32.5 | 140.0 | 71.2 | ||
| Sex | |||||||
| Male | 54 | 65.0 | 27.5 | 0.948 | 127.5 | 66.9 | 0.637 |
| Female | 27 | 65.0 | 30.0 | 130.0 | 80.0 | ||
| Tumour type | |||||||
| SCC | 62 | 65.0 | 26.2 | 0.231 | 130.0 | 70.0 | 0.571 |
| Adeno | 19 | 50.0 | 30.0 | 125.0 | 115.0 | ||
| Tumour volume | |||||||
| <Median | 20 | 70.0 | 42.5 | 0.738 | 140.0 | 93.8 | 0.974 |
| ≥Median | 27 | 65.0 | 25.0 | 140.0 | 70.0 | ||
| Tumour stage (UICC) | |||||||
| I | 45 | 60.0 | 30.0 | 125.0 | 85.0 | ||
| II | 14 | 70.0 | 32.5 | 0.212 | 140.0 | 63.7 | 0.504 |
| IIIa | 22 | 65.0 | 65.0 | 135.0 | 75.6 | ||
| TNM-T | |||||||
| T1 | 27 | 70.0 | 35.0 | 140.0 | 75.0 | ||
| T2 | 44 | 62.5 | 28.8 | 0.983 | 125.0 | 75.6 | 0.952 |
| T3 | 10 | 65.0 | 31.2 | 135.0 | 63.8 | ||
| TNM-N | |||||||
| N0 | 50 | 65.0 | 26.2 | 127.5 | 72.5 | ||
| N1 | 15 | 70.0 | 40.0 | 0.231 | 140.0 | 75.0 | 0.571 |
| N2 | 16 | 55.0 | 25.0 | 120.0 | 69.4 | ||
| Outcome | |||||||
| Dead | 48 | 65.0 | 25.0 | 0.543 | 120.0 | 71.9 | 0.389 |
| Alive | 33 | 55.0 | 32.5 | 140.0 | 80.0 | ||