Adenocarcinoma | Mesothelioma | |||||
---|---|---|---|---|---|---|
Antibody/antigen | Positive (%) | Negative (%) | Staining pattern | Positive (%) | Negative (%) | Staining pattern |
SPA-1, surfactant apoprotein A; TTF-1, thyroid transcription factor 1. | ||||||
Calretinin | 6 | 94 | Cytoplasm and nuclei | 80 | 20 | Cytoplasm and nuclei |
Cytokeratin 5/6 | 6 | 94 | Pericellular and cytoplasm | 63 | 37 | 72% pericellular and cytoplasmic, 28% cytoplasm only |
E-cadherin | 100 | 0 | Cell membrane | 22 | 78 | Cell membrane |
N-cadherin | 26 | 74 | 22% cell membrane, 78% cytoplasm | 78 | 22 | 22% membrane, 31% cytoplasm, 47% both |
SP-A | 100 | 0 | 26% cell membrane, 74% cytoplasm | 98 | 2 | 82% membrane, 18% cytoplasm |
Thrombomodulin | 6 | 94 | Cell membrane | 53 | 47 | Cell membrane |
TTF-1 | 69 | 31 | Nuclear | 0 | 100 |