NISH | PCR | |||||||
---|---|---|---|---|---|---|---|---|
HPV E6, type specific† | ||||||||
Case No. | HPV type | Signal type | HPV L1 | HPV E6/E7 (benign group) | HPV E6/E7 (malignant group) | HPV E6/E7, type specific* (HPV type) | HPV-16 | HPV-18 |
HPV types 6, 11, 31, and 33 were not detected with NISH. | ||||||||
*HPV types 6, 11, 31, 33, 52b, and 58 were not detected with this restriction endonuclease digestion system; †HPV type 33 not detected. | ||||||||
NISH, non-isotopic in situ hybridisation; PCR, polymerase chain reaction. | ||||||||
1 | 16 | 2 | + | − | − | − | ||
2 | Negative | − | − | − | − | − | ||
3 | 16 | 2, 3 | + | − | + | 16 | + | − |
4 | Negative | − | − | − | − | − | ||
5 | Negative | + | − | − | + | − | ||
6 | Negative | − | − | − | − | − | ||
7 | 16 | 2, 3 | + | − | + | 16 | + | − |
8 | Negative | + | − | + | 16 | + | − | |
9 | 18 | 2 | + | − | + | 18 | − | + |
10 | Negative | + | − | + | 18 | − | + | |
11 | 16 | 2 | + | − | + | 16 | + | − |
12 | 16 | 2 | + | − | + | 16 | + | − |