Non-culture confirmation of meningococcal disease 1993–9
| II | III | IV | V | VI | VII | |||||||||||
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| Year | GNdC in CSF | GNdC in skin | Positive | B | C | Serum | CSF | Plasma | Other | B | C | Y | W135 | NK | Throat swab | Antibody titre |
| Diagnostic categories: I, culture confirmed from blood, CSF or other sterile site; II, Gram negative diplococci in CSF in clinical meningitis; III, Gram negative diplococci in skin aspirate in clinical septicaemia; IV, clinical meningitis: PCR positive CSF or blood; V, clinical meningitis: antigen positive CSF; VI, clinical meningitis or septicaemia: positive throat swab; VII, clinical meningitis or septicaemia: positive serology. | ||||||||||||||||
| GndC, Gram negative diplococci; CSF, cerebrospinal fluid; B, C, Y and W135 relate to meningococcal capsule serogroups; NK, not known. | ||||||||||||||||
| 1993 | 3 | – | – | – | – | – | – | – | – | – | – | – | – | – | – | 0 |
| 1994 | 12 | 2 | – | – | – | – | – | – | – | – | – | – | – | – | 1 | 10 |
| 1995 | 6 | 5 | 45 | 5 | 5 | 7 | 37 | 1 | – | – | – | 1 | – | – | 6 | 16 |
| 1996 | 6 | 2 | 32 | 8 | 4 | 8 | 22 | 2 | – | 3 | 2 | 1 | – | 3 | 16 | 17 |
| 1997 | 14 | 1 | 29 | 8 | 10 | 5 | 24 | – | – | – | – | – | – | – | 6 | 12 |
| 1998 | – | 2 | 43 | 16 | 15 | 17 | 26 | – | – | – | 3 | – | – | – | 18 | 21 |
| 1999 | 2 | 4 | 37 | 18 | 9 | 11 | 23 | 2 | 1 | – | 3 | – | – | – | 21 | 42 |