Table 5
Treatment of HCV associated mixed cryoglobulinaemia
| Proposed treatments | |||
|---|---|---|---|
| *α Interferon + ribavirin. | |||
| NHL, non-Hodgkin's lymphoma; HCC, hepatocellular carcinoma; HCV, hepatitis C virus; LAC, low antigen content. | |||
| Asymptomatic | None |
| |
| Mild–moderate manifestations | |||
| Purpura, weakness, | Low dose steroids | ||
| arthralgias, arthritis, | and/or LAC diet, | ||
| peripheral sensory neuropathy | other symptomatics | ||
| Attempt at HCV eradication* | |||
| Severe manifestations | |||
| Nephropathy, skin ulcers, | Steroids, | ||
| sensory motor neuropathy, | and/or plasma exchange, | ||
| widespread vasculitis | and/or cyclophosphamide | ||
| Active hepatitis | α Interferon + ribavirin | ||
| Cancer | |||
| B cell NHL, HCC | Chemotherapy, surgery | ||