Reactivities of primary tumours, recurrences, and metastases
| Hormone | Primary 1986 | 1° recurrence 1991 | 2° recurrence 1993 | Frontal metastasis | Temporal metastasis | Spinal metastasis |
|---|---|---|---|---|---|---|
| ACTH, adrenocorticotrophin; AgNOR, argyrophilic nucleolar organiser region; Foc, focal; FSH, follicle stimulating hormone; GH, growth hormone; LH, luteinising hormone; ND, not determined; Neg, negative; PCNA, proliferating cell nuclear antigen; Pos, positive; PRL, prolactin; TSH, thyroid stimulating hormone. | ||||||
| *Postmortem specimen. | ||||||
| PRL | Pos | Neg | Neg | Foc* | Foc* | Foc* |
| ACTH | Neg | Pos | Neg | Pos | Pos | Pos |
| GH | Neg | Neg | Neg | Foc* | Neg | Neg |
| LH | Neg | Neg | Neg | Neg | Neg | Neg |
| FSH | Neg | Neg | Neg | Neg | Neg | Neg |
| TSH | Neg | Neg | Neg | Neg | Neg | Neg |
| PHE5 | Neg | Neg | Neg | Neg | Neg | Neg |
| CHRA | Pos | Pos | Pos | Pos | Nos | Pos |
| SY38 | Pos | Pos | Pos | Pos | Pos | Pos |
| MIB1 | 1.53% | 1.64% | 1.20% | 6.25% | 6.05% | Neg |
| PCNA | Neg | ND | 22.07% | ND | 78.00% | Neg |
| p53 | Neg | ND | Neg | Neg | 4.37% | Neg |
| AgNOR | 01:22 | ND | 4.51% | 2.36% | ND | ND |