N | P16INK4A staining intensity | HPV -ive | HPV-6/11 | HPV-16 | HPV-18 | HPV-31 | HPV-33 | |
---|---|---|---|---|---|---|---|---|
Not all cases included in our study were evaluated for HPV status. Staining intensity: 0, no positive p16INK4A staining; 1, <10% positive p16INK4A staining; 2, >10% but <50% positive p16INK4A staining; 3, >50% positive p16INK4A staining. | ||||||||
CIN, cervical intraepithelial neoplasia; cGIN, cervical glandular intraepithelial neoplasia; N, number of cases tested for HPV. | ||||||||
Normal | 20 | 0 | 18/20 (90%) | 2/20 (10%) | – | – | – | – |
1 | – | – | – | – | – | – | ||
2 | – | – | – | – | – | – | ||
3 | – | – | – | – | – | – | ||
Total | 90% | 10% | ||||||
cGIN | 3 | 0 | – | – | – | – | – | – |
1 | – | – | – | – | – | – | ||
2 | – | – | – | – | – | – | ||
3 | – | – | 3/3 (100%) | – | – | – | ||
Total | 100% | |||||||
CIN 1 | 29 | 0 | – | – | – | – | – | – |
1 | 2/29 (7%) | 3/29 (10%) | – | – | – | – | ||
2 | 2/29 (7%) | 1/29 (4%) | – | – | – | – | ||
3 | – | – | 21/29 (72%) | – | – | – | ||
Total | 14% | 14% | 72% | |||||
CIN2 | 28 | 0 | – | – | – | – | – | – |
1 | 3/28 (11%) | 2/28 (7%) | – | – | – | – | ||
2 | – | – | 8/28 (28%) | 1/28 (4%) | – | – | ||
3 | – | – | 14/28 (50%) | – | – | – | ||
Total | 11% | 7% | 78% | 4% | ||||
CIN3 | 36 | 0 | 1/36 (3%) | – | – | – | – | – |
1 | 1/36 (3%) | 1/36 (3%) | – | – | – | – | ||
2 | 1/36 (3%) | – | 8/36 (22%) | 2/36 (5%) | – | – | ||
3 | – | – | 20/36 (56%) | 2/36 (5%) | – | – | ||
Total | 9% | 3% | 78% | 10% | ||||
Invasive | 9 | 0 | – | – | – | – | – | – |
1 | – | – | – | – | – | – | ||
2 | – | – | – | – | – | – | ||
3 | – | – | 9/9 (100%) | – | – | – | ||
Total | 100% |