Criteria for immunohistochemical staining with anti-α-methylacyl CoA racemase (AMACR/P504S) that would support a diagnosis of malignancy on prostate needle biopsies
| Intense staining easily visible on low power examination |
| Circumferential, granular, luminal (apical) to diffuse cytoplasmic staining of acini with malignant features on haematoxylin and eosin sections |
| Negative staining or weak, non-circumferential staining in adjacent benign glands |