Genes involved in human systemic lupus erythematosus
| HLA, human leucocyte antigen; Sm, Smith antigen. |
| HLA genes |
| DR2, DR3 (relative risk 2–5) |
| DR2, DR3, DR7, DQw1, DQw2, DQA1, DQB1, B8 (anti-Ro) |
| DR3, DR8, DRw12 (anti-La) |
| DR3, DQw2, DQA1, DQB1, B8 (anti-Ro and anti-La) |
| DR2, DR3, DR7, DQB1 (anti-DNA) |
| DR2, DR4, DQw5, DQw8, DQA1, DQB1 (anti-U1 ribonuclear protein) |
| DR2, DR4, DR7, DQw6, B61 (anti-Sm) |
| DR4, DR7, DQ6, DQ7, DQw7, DQw8, DQw9 (anticardiolipin or lupus anticoagulant) |
| Complement genes (C2, C4, C1q) |
| Non-HLA genes |
| Mannose binding lectin polymorphisms |
| Tumour necrosis factor α |
| T cell receptor |
| Interleukin 6 |
| CR1 |
| Immunoglobulin Gm and Km |
| FcγRIIA (IgG Fc receptor) |
| FcγRIIIA (IgG Fc receptor) |
| PARP (poly-ADP ribose polymerase) |
| Heat shock protein 70 |
| Humhr 3005 |