Patient | Normalised values of PCR target detected by MGB probe* (those by non-MGB probe) | ||||
---|---|---|---|---|---|
Initial diagnosis | 15 days | 1 month | 3 months | 4 months | |
ALL, acute lymphoblastic leukaemia; blank, not determined; MGB, minor groove binder; RQ-PCR, real time quantitative polymerase chain reaction; –, not detected. | |||||
*The normalised values of targets were expressed as the ratio of the target copy number for each 105 cell equivalent from the integrated standard curves of human β actin, as described previously.4 | |||||
1 | 42700 (38000) | 0.34 (–) | – (–) | – (–) | 1.36 (0.74) |
2 | 17500 (11700) | 17.6 (15.4) | – (–) | – (–) | |
3 | 38200 (29400) | 14060 (16500) | 1280 (687) | – (–) | – (–) |
4 | 27100 (30300) | 33400 (34800) | – (–) | – (–) | |
5 | 15300 (9050) | 336 (425) | – (–) | ||
6 | 8700 (10700) | 870 (440) | |||
7 | 3160 (320) | 35.0 (57.0) | |||
8 | 7700 (4100) | 1.42 (0.73) | |||
9 | 69500 (68000) | 8550 (8400) | 5.84 (9.10) | ||
10 | 3350 (4540) | 210 (180) | |||
11 | 29000 (32800) | – (–) | – (–) | ||
12 | 19800 (20800) | 10.5 (7.6) | – (–) | ||
13 | 4840 (4290) | – (–) | – (–) | – (–) | |
14 | 2330 (2480) | – (–) | – (–) | ||
15 | 770 (535) | – (–) | – (–) | – (–) | |
16 | 23000 (18300) | – (–) | – (–) | ||
17 | 1250 (1430) | 6200 (530) | 350 (340) | ||
18 | 12830 (11250) | 17.4 (12.4) | – (–) | 4.9 (0.74) |