Options for warfarin reversal
| Type of reversal | Approach |
|---|---|
| FFP, fresh frozen plasma; IV, intravenous; PCC, prothrombin complex concentrate. | |
| Rapid (complete; within 10–15 minutes) | PCC (immediate replacement of vitamin K dependent coagulation factors) plus IV vitamin K (switch on hepatic synthesis within a few hours) |
| Fast (partial) | FFP (immediate replacement of vitamin K dependent coagulation factors—but the correction of the coagulopathy is partial) |
| Prompt (within 4–6 hours) | IV vitamin K |
| Slow (within 24 hours) | Oral vitamin K |
| Ultraslow (over days) | Omit warfarin dose (no vitamin K) |