Case 1 | Case 2 | |
---|---|---|
+, almost all neoplastic cells positive; +/−, most neoplastic cells positive; −/+, minority of neoplastic cells positive; −*, few neoplastic cells positive; −, all neoplastic cells negative; NE, not evaluable. | ||
AQP3, aquaporin 3; CIgG, cytoplasmic IgG; CLA, common leucocyte antigen; EBER, Epstein-Barr virus encoded small non-coding RNA; EBNA-1, Epstein-Barr virus nuclear antigen 1; EMA, epithelial membrane antigen; HHV-8, human herpesvirus type 8; IHC, immunohistochemistry; ISH, in situ hybridisation; KSHV, Kaposi sarcoma associated herpesvirus; ORF, open reading fragment; PCR, polymerase chain reaction; SELPLG, selectin P ligand; syn-1, syndecan 1; VEGF, vascular endothelial growth factor. | ||
KSHV (IHC) | ORF73+ | ORF73+ |
vIL-6− | vIL-6+ | |
KSHV (PCR) | KS330+ | KS330+ |
ORF72+ | ORF72+ | |
ORF9-3+ | ORF9-3− | |
EBER (ISH) | − | + |
EBNA-1 (PCR) | − | + |
LMP1 (IHC) | − | − |
CLA/CD45 | − | −/+ |
EMA | + | −* |
MUM1/IRF4 | + | + |
CD138/syn-1 | + | −/+ |
VS38c | −/+ | + |
CD30 | −/+ | − |
ALK (ALK1) | − | − |
CD20 | − | − |
CD40 | − | − |
CD79a | − | − |
CD3 | −/+ | − |
CD5 | − | − |
CD43 | −/+ | −/+ |
CD45RO | − | − |
CD10 | − | − |
Ki-67/MIB1 | + | + |
κ/λ chain | − | − |
CIgG | + | + |
CD15 | − | − |
CD68 | − | − |
S100 | − | − |
Keratin (AE1/AE3) | − | − |
Keratin (MNF116) | − | − |
Granzyme A | −/+ | −* |
AQP3 | −* | + |
SELPLG | + | + |
VEGF | + | + |