Calretinin staining* | S100 staining in nerve fibres | NSE staining in ganglionic cells | Abnormal c-kit staining | ||
---|---|---|---|---|---|
Ganglionic cells | Nerve fibres | ||||
*Includes submucosal and myenteric plexus. | |||||
Hirschsprung’s disease; NSE, neurone specific enolase. | |||||
Ganglionic segment | 24/24 | 24/24 | 24/24 | 24/24 | 4/24 |
Aganglionic segment | No ganglion cells | 0/17 | 17/17 | 0/17 | 17/17 |
Transitional zone | 10/13 | 12/13 | 13/13 | 12/13 | 10/13 |