Immunohistochemistry results
| Antibody | Category | Morules | SD |
|---|---|---|---|
| Categories: A, epithelial antigens; B, nerve and neuropeptide related antigens; C, oncofetal and proliferative cell related antigens; D, intermediate filaments; E, others. | |||
| –, Immunohistochemical staining negative in all cases; −/+, both negative and positive cases were seen; +, all cases positively stained; *, a sporadic positive reaction was found in 3 cases; †, a sporadic positive reaction was seen in one case. | |||
| Apo-A, apolipoprotein A; CEA, carcinoembryonic antigen; CK, cytokeratin; EMA, epithelial membrane antigen; GFAP, glial fibrillary acidic protein; NSE, neurone specific antigen; PCNA, proliferating cell nuclear antigen; SD, squamous differentiation; VIP, vasoactive intestinal polypeptide | |||
| CK AE1/AE3 | A | – | + |
| CK5/6 | A | – | −/+ |
| CK7 | A | – | −/+ |
| CK10 | A | – | −/+ |
| CK14 | A | – | −/+ |
| CK17 | A | – | – |
| CK19 | A | – | −/+ |
| CK LP 34 | A | – | – |
| Involucrin | A | – | + |
| EMA | A | – | + |
| NSE | B | + | – |
| Acetylcholine esterase* | B | −/+ | −/+ |
| S-100* | B | −/+ | – |
| GFAP | B | – | – |
| Chromogranin A | B | – | – |
| Synaptophysin† | B | – | – |
| Somatostatin | B | −/+ | – |
| Enkephalin | B | – | – |
| Serotonin | B | – | – |
| Calcitonin | B | – | – |
| VIP | B | – | – |
| Insulin | B | – | – |
| Glucagon | B | – | – |
| CEA | C | – | −/+ |
| p53 | C | – | −/+ |
| PCNA | C | – | + |
| Ki-67 | C | – | −/+ |
| c-kit | C | – | – |
| CD34 | C | – | – |
| Apo-A | C | – | – |
| Blood group A | C | – | – |
| Blood group B | C | – | −/+ |
| Blood group AB | C | – | −/+ |
| Desmin | D | – | – |
| Vimentin | D | – | – |
| α Smooth muscle actin | D | – | – |
| Oestrogen receptor | E | – | – |
| Progesterone receptor | E | – | + |
| β Catenin | E | −/+ | −/+ |