Multivariate Cox predictive model for all CHD related events involving backward stepwise logistic regression
| Variables | Multivariate Cox predictive model for all CHD related events | |
|---|---|---|
| HR (95% CI) | p Value | |
| Nineteen univariate predictors of all CHD related events all with p<0.10 (the above plus: male sex, female sex, current smoking, family history of premature CAD, history of hypertension, history of diabetes mellitus, previous revascularisation, acute coronary syndrome, and previous myocardial infarction) were initially entered (n = 1600, 292 events). | ||
| ACE, angiotensin converting enzyme; CAD, coronary artery disease; CHD, coronary heart disease; CI, confidence interval; CrCl, creatinine clearance; HDL-C, high density lipoprotein cholesterol; HR, hazards ratio; LDL-C, low density lipoprotein cholesterol. | ||
| Age (years) | 1.07 (1.02 to 1.11) | 0.02 |
| Statin treatment | 0.51 (0.39 to 0.66) | <0.0001 |
| On treatment LDL-C <2.6 mmol/l | 0.67 (0.49 to 0.84) | <0.0001 |
| On treatment LDL-C >3.6 mmol/l | 1.32 (1.13 to 1.56) | <0.0001 |
| On treatment HDL-C >1.0 mmol/l | 0.87 (0.79 to 0.94) | 0.002 |
| On treatment HDL-C <1.0 mmol/l | 1.12 (1.04 to 1.28) | 0.005 |
| CrCl (with every 5% increase) | 0.84 (0.73 to 0.95) | 0.003 |
| CrCl (with every 5% reduction) | 1.10 (1.03 to 1.21) | 0.01 |
| Use of β blockers during study | 0.72 (0.58 to 0.89) | <0.0001 |
| Use of ACE inhibitors during study | 0.84 (0.69 to 0.96) | 0.01 |