Distribution of F-RBC in germ cell tumours
| No | Sex | Organ | Tumour | F-RBC distribution | Comment |
|---|---|---|---|---|---|
| AFT, α fetoprotein; EC, embryonal carcinoma; F-RBC, fetal haemoglobin positive red blood cells; hCG, human chorionic gonadotrophin; MMT, metastatic mature teratoma; NMT, non-metastatic mature teratoma; TD, trophoblastic disease; YS, yolk sac. | |||||
| 1 | Male | Testis | EC | Congested (30%) F-RBC in blood lakes surrounding the tumour cells (fig 2A) | hCG and AFP negative |
| 2 | Male | Testis | EC | Positive as in 1. Also 2–5% F-RBC in blood vessels | No F-RBC in the counterpart normal testis |
| 3 | Male | Retroperitoneal lymph node | EC | Positive as in 2 | |
| 4 | Male | Testis | EC | None | hCG and AFP positive |
| 5 | Male | Brain | MMT | Congested (30%) F-RBC in blood lakes and haemorrhagic zones (fig 2B) in blood vessels 5% | hCG positive AFP negative |
| 6 | Female | Brain | MMT | Positive as in 5 | |
| 7 | Male | Retroperitoneal lymph node | MMT | None | |
| 8 | Male | Testis | MMT | none | |
| 9 | Female | Ovary | Mixed germinoma and YS | In germinoma positive as in 1. In YS none | AFP positive in YS. hCG negative |
| 10–14 | Male | Testis | NMT | None | |
| 15 | Male | Brain | Mixed seminoma and mature teratoma | None | |
| 16 | Female | Lymph node | Mixed YS and mature teratoma | None | AFP positive in YS |
| 17 | Female | Ovary | Dermoid cyst | Positive as in 2 | |
| 18–26 | Female | Ovary | Dermoid cyst | None | |