Distribution of p53 genotypes in patients with cervical cancer and normal controls
| Locus | Population (N) | p53 genotype | χ2HW | |||
|---|---|---|---|---|---|---|
| 1–1 (%) | 2–1 (%) | 2–2 (%) | p Value | |||
| N is the number of individuals analysed. | ||||||
| 1 at an individual locus indicates the absence of a 16 bp duplication at intron 3, a proline at Bst UI, and the absence of Nci I at intron 6. | ||||||
| 2 at individual locus indicates the presence of a 16 bp duplication at intron 3, an arginine at Bst UI, and the presence of Nci I at intron 6. | ||||||
| χ2HW stands for χ2 for deviation from Hardy-Weinberg equilibrium. | ||||||
| 16 bp (intron3) | Cases (61) | 45 (73.8) | 15 (24.6) | 1 (1.6) | 0.528 | 0.04 |
| Control (93) | 61 (65.6) | 29 (31.2) | 3 (3.2) | 0.04 | ||
| Bst UI (Arg/Pro) | Cases (61) | 12 (19.7) | 30 (49.2) | 19 (31.1) | 0.038 | 0 |
| Control (94) | 29 (30.8) | 51 (54.2) | 14 (15.0) | 1.21 | ||
| Nci I (intron6) | Cases (52) | 1 (1.9) | 16 (30.8) | 35 (67.3) | 0.687 | 0.29 |
| Control (84) | 3 (3.6) | 30 (35.7) | 51 (60.7) | 0.31 | ||