Polymorphisms associated with advanced prostate cancer risk
| Gene | Chromosomal locus | Function |
|---|---|---|
| Vitamin D receptor | 13q | Promotes the differentiation and growth arrest of prostate cancer cells in vitro |
| CDKN1A (p21) | 6p | Belong to the Cip/Kip family and functions as an important cell cycle gatekeeper |
| CDKN1B (p27) | 12p |