Abstract P15
| mRNA species | Extracellular matrix (solid phase) | Albumin (soluble phase) | |||||
|---|---|---|---|---|---|---|---|
| Matrix control | Glycated matrix | AG matrix | BSA control | AGE-BSA | AG-BSA | ||
| Values are mean (SD). | |||||||
| *p<0.05 v control. | |||||||
| AG, aminoguanidine; AGE, advanced glycation end products; BSA, bovine serum albumin; CTGF, connective tissue growth factor; TGFβ1, transforming growth factor β1. | |||||||
| CTGF | 100% (17%) | 148% (10%)* | 84.4 (12%) | 100% (7.5%) | 136% (12%)* | 90.8% (3.2%) | |
| TGFβ1 | 100% (17%) | 62.8% (6.2%)* | 94.2% (14%%) | 100% (19%) | 276% (8.4%)* | 110% (2.9%) | |