Table 3

Chromosomal and gene characteristics according to stage and lymph node status

Variable		No. cases	T3–4	p Value	No. cases	Node +	p Value
Significance was assessed using the χ² test. Those values underlined showed a positive trend when chromosomal and gene characteristics were compared with T3–4 stage and lymph nodal involvement, even though the results were not significant.
*Median value.
NS, not significant.
Monosomy 3	⩽18*	22	40.9	0.03	20	35.0	NS
Monosomy 3	>18*	20	75.0	0.03	20	50.0	NS
Polysomy 3	⩽18*	20	65.0	NS	19	42.1	NS
Polysomy 3	>18*	22	50.0	NS	21	42.9	NS
Aneusomy 3	⩽54*	23	60.9	NS	22	40.9	NS
Aneusomy 3	>54*	19	52.6	NS	18	44.4	NS
Monosomy 7	⩽19*	23	43.5	0.04	22	27.3	NS
Monosomy 7	>19*	20	75.0	0.04	20	55.0	NS
Polysomy 7	⩽22*	21	61.9	NS	21	42.9	NS
Polysomy 7	>22*	22	54.5	NS	21	38.1	NS
Aneusomy 7	⩽48*	22	63.6	NS	22	50.0	NS
Aneusomy 7	>48*	21	52.4	NS	20	30.0	NS
Monosomy 9	⩽22*	23	47.8	NS	22	27.3	NS
Monosomy 9	>22*	21	66.7	NS	20	50.0	NS
Polysomy 9	⩽2*	22	59.1	NS	20	40.0	NS
Polysomy 9	>2*	22	54.5	NS	22	36.4	NS
Aneusomy 9	⩽38*	25	60.0	NS	24	41.7	NS
Aneusomy 9	>38*	19	52.6	NS	18	33.3	NS
Monosomy 17	⩽18*	21	42.9	0.04	20	30.6	NS
Monosomy 17	>18*	23	69.6	0.04	23	47.8	NS
Polysomy 17	⩽12*	23	65.2	NS	22	45.5	NS
Polysomy 17	>12*	21	47.6	NS	21	33.3	NS
Aneusomy 17	⩽44*	21	61.9	NS	20	50.0	NS
Aneusomy 17	>44*	23	52.2	NS	23	30.4	NS
RB heterozygous	⩽26*	25	44.0	0.03	23	26.1	NS
RB heterozygous	>26*	23	73.9	0.03	23	52.2	NS
9p21 heterozygous	⩽24*	21	47.6	NS	19	36.8	NS
9p21 heterozygous	>24*	19	63.2	NS	19	36.8	NS
p53 heterozygous	⩽28*	21	57.1	NS	21	33.3	NS
p53 heterozygous	>28*	18	61.9	NS	16	56.3	NS
RB homozygous	No	27	66.7	NS	26	38.5	NS
RB homozygous	Yes	21	47.6	NS	20	40.0	NS
9p21 homozygous	No	11	36.4	NS	11	27.3	NS
9p21 homozygous	Yes	29	62.1	NS	27	40.7	NS
p53 homozygous	No	25	56.0	NS	25	44.0	NS
p53 homozygous	Yes	14	64.3	NS	12	41.7	NS
HER-2	<2	36	556	NS	35	40.0	NS
HER-2	>2	7	51.7	NS	7	28.6	NS