Histological, histochemical, and immunohistochemical findings
| Case | Granuloma location | Histology | CD4/CD8* | Ziehl-Neelsen | PAS | Fite-Faraco | TBC-PCR |
|---|---|---|---|---|---|---|---|
| *Within the granulomas. | |||||||
| BM, bone marrow; CLL, small lymphocytic lymphoma/chronic lymphocytic leukaemia; LN, lymph node; PAS, periodic acid schiff; PCR, polymerase chain reaction; TBC, tuberculosis. | |||||||
| 1 | BM | Microgranuloma, no giant cells; CLL | 1/1 | Negative | Negative | Negative | Negative |
| 2 | LN | Circumscribed granulomas, epithelioid and Langhans giant cells; CLL | 5/1 | Negative | Negative | Negative | Negative |
| 3 | BM | Circumscribed granulomas, epithelioid cells, no giant cells; CLL | 10/1 | Negative | Negative | Negative | Negative |
| 4 | LN | Necrotising granulomas, epithelioid and Langhans giant cells; CLL | 2/1 | Positive | Negative | Negative | Positive |
| 5 | LN | Large granulomas, foamy macrophages; CLL | No T cells | Positive | Positive | Positive | Negative |