Relation between HER-2 overexpression determined by immunohistochemistry and immunocytochemistry and gene amplification detected by CISH in cytology
| Immunohistochemistry | ||||
|---|---|---|---|---|
| Negative (0, 1+) | Indeterminate(2+) | Positive (3+) | Total | |
| CISH, chromogenic in situ hybridisation. | ||||
| Immunocytochemistry | ||||
| Negative (0, 1+) | 72 | 3 | 0 | 75 |
| Indeterminate (2+) | 1 | 8 | 4 | 13 |
| Positive (3+) | 0 | 1 | 5 | 6 |
| Total | 73 | 12 | 9 | 94 |
| CISH in cytology | ||||
| No amplification (2–6) | 69 | 3 | 0 | 72 |
| Low amplification (6–10) | 4 | 7 | 0 | 11 |
| High amplification (>10) | 0 | 2 | 9 | 11 |
| Total | 73 | 12 | 9 | 94 |