Table 3 Frequencies and types of BRCA2 familial mutations

Exon no	Familial mutation	No of individuals (%) withBRCA2* mutations (n = 25)
11	6714_6717delACAA	2 (11.8)
	6503delTT	1 (5.9)
	6174delT	1 (5.9)
	6137C>A (S1970X)	2 (11.8)
	5950delCT	2 (11.8)
	5368delATTT*	1 (5.9)
	5056insG*	3 (17.6)
	4859insA	2 (11.8)
	4329insA*	1 (5.9)
	4329delA*	1 (5.9)
	3386T>G (L1053X)	1 (5.9)
	3036delACAA	1 (5.9)
	Total	18
2	295G>T	4 (100)
	Total	4
23	9138insA*	1
	Total	1
8	860–1G>A*	2 (100)
	Total	2