Table 5 Cancer sites in relation to BRCA1 and BRCA2 mutations

Cancer site*	Mutation inBRCA1	Mutation inBRCA2	Total	p Value†
Breast	54	9	63	0.001
Ovary	12	0	12
Breast and ovary	13	2	15
Breast or ovary and other sites	0	2	2
Other sites	0	1	1
Total	79	14	93

*Site was unknown for five of 98 patients with cancer (three with exon 11, and two other exon mutations in the BRCA1 gene).
†Calculated using two-sided Fisher’s exact test.