Table 7 Cox regression analysis between specific BRCA1 exon mutation and age at diagnosis
MutationHazard ratioStandard errorp Value (95% CI)
Exon 110.690.210.2 (0.38 to 1.25)
Exon 20.280.09<0.001 (0.15 to 0.54)
Exon 131.160.510.7 (0.49 to 2.75)

  • Hazard ratio of <1 indicates lower hazard than the other groups and hence older ages at diagnosis.