Table 4

Association of connective tissue growth factor (CTGF) and cysteine rich-61 (Cyr61) protein levels with clinicopathological parameters in colorectal cancer cases

Clinicopathological parameters	Intensity of CTGF staining			Cyr61 staining
Clinicopathological parameters	N	Mean (±SD)	p Value	N	Mean (±SD)	p Value
Dukes' stage
A	10	1.200 (0.919)	0.006^* ^†	10	1.800 (0.919)	0.243^†
B	11	1.818 (0.982)	0.002^§	5	2.800 (1.304)	0.226^§
C	18	2.388 (0.607)		13	2.461 (1.266)
T stage
1 and 2	11	1.273 (0.905)	0.009^* ^‡	10	1.800 (0.919)	0.133^‡
3 and 4	28	2.179 (0.819)		18	2.556 (1.247)
Node status
0	21	1.524 (0.981)	0.004^* ^‡	15	2.133 (1.125)	0.473^‡
1 and 2	18	2.389 (0.608)		13	2.462 (1.266)
Tumour differentiation
Well	6	1.667 (0.816)	0.630^†	6	2.333 (0.817)	0.692^†
Moderate	25	1.920 (0.996)	0.360^§	15	2.133 (1.246)	0.750^§
Poor	8	2.125 (0.834)		7	2.571 (1.397)
Extramural vascular invasion
No	30	1.833 (0.949)	0.285^†	22	2.227 (1.152)	0.642^†
Yes	9	2.222 (0.833)		6	2.500 (1.378)

Mean CTGF and Cyr61 protein expression values and SD are included here with clinicopathological parameters.
↵* Statistical significance is when p<0.05.
↵† Kruskal–Wallis test.
↵‡ Mann–Whitney test.
↵§ Jonckheere–Terpstra test.