Table 1

Main laboratory tests for the assessment of iron depletion

Laboratory testNormal values
Conventional unitsConversion factor SI units
Iron status in the body
▶Serum iron50–180 μg/dl×0.1799–32 μmol/l
▶Transferrin200–360 mg/dl×0.012–3.6 g/l
▶Transferrin saturation20–50%
▶Ferritin (Ft)30–300 ng/ml×2.24765–670 pmol/l
▶Soluble transferrin receptors (sTfR)* 0.76–1.76 mg/l 6.4–25.7 nmol/l
▶Ratio of sTfR to serum Ft (sTfR/log Ft)<1
Iron-deficient red cell production
▶Haemoglobin12–16 g/dl (women); 13–17 g/dl (men)×0.6206 7.5–10 mmol/l (women); 8–10.5 mmol/l (men)
▶Mean corpuscular volume80–100 fl
▶Red cell distribution width11–15
▶Mean corpuscular haemoglobin28–35 pg
▶Hypochromic red cells<5%
▶Reticulocyte haemoglobin content28–35 pg
  • * Normal values may differ depending on the assay used.

  • To convert the concentration values in conventional units into SI units multiply values by the conversion factor.

  • In fact, although widely used, this factor allows for the calculation the molar concentration of haemoglobin subunits. Thus, the molar concentration of haemoglobin (molecular mass 64 kDa) is fourfold lower (2–3 mmol/l).