Differences between adults and children with ulcerative colitis
| Age group with higher prevalence | Feature | Additional details | References |
|---|---|---|---|
| Children | Pancolitis/subtotal colitis | Children 42%; adults 11% | 48 |
| Normal architecture/no crypt distortion | 0% of adults in one study | 28 38 48 | |
| Patchy chronic changes/patchy inflammation | Children>adults; or children only (21%) | 38 48 | |
| Children/neither | Rectal sparing | 28 38 48 | |
| Adults | Diffuse continuous disease | Adults 100%; children 68% | 48 |
| Diffuse crypt abnormalities within a biopsy | Adults 58%; children 32% | 28 | |
| Crypt atrophy | Adults 67%; children 33% | 28 | |
| Severe crypt atrophy | Adults 21%; children 6% | 28 | |
| Plasma cells in lamina propria | 31 | ||
| Adults/neither | Cryptitis and crypt abscesses | 28 31 | |
| Crypt branching | 28 31 |
Site biopsied: rectal biopsy28; rectosigmoid biopsies38; sigmoidoscopy or colonoscopy.48