Expression of membranous full-length (EpCAMMF) EpCAM and the truncated variant (EpCAMMT) in EpEX-positive tumours
| Tumour entity | EpCAMMF | EpCAMMT | χ2 | ||
|---|---|---|---|---|---|
| n | % | n | % | ||
| Pancreatic cancer (n=20) | 13 | 65 | 7 | 35 | NA |
| Prostate cancer (n=42) | 41 | 97.6 | 1 | 2.4 | NA |
| Oesophageal cancer (n=15) | 10 | 66.7 | 5 | 33.3 | NA |
| Mesothelioma (n=4) | 4 | 100 | 0 | 0 | NA |
| Gallbladder cancer (n=26) | 22 | 84.6 | 4 | 15.4 | NA |
| Cervical cancer (n=5) | 4 | 80 | 1 | 20 | NA |
| Laryngeal cancer (n=5) | 5 | 100 | 0 | 0 | NA |
| Hepatocellular carcinoma (n=6) | 5 | 83.3 | 1 | 16.7 | NA |
| Colon | |||||
| Low-grade dysplasia (n=37) | 34 | 91.9 | 3 | 8.1 | 0.024 |
| High-grade dysplasia (n=80) | 66 | 82.5 | 14 | 17.5 | |
| Adenocarcinoma (n=33) | 22 | 66.7 | 11 | 33.3 | |
| Stomach | |||||
| Intestinal type cancer (n=35) | 19 | 54.3 | 16 | 45.7 | 0.180 |
| Diffuse cancer (n=9) | 6 | 66.7 | 3 | 33.3 | |
| Mixed histology (n=3) | 2 | 33.3 | 1 | 66.7 | |
| Small intestine cancer (n=14) | 9 | 64.3 | 5 | 35.7 | NA |
| Endometrium | |||||
| Endometrioid carcinoma (n=32) | 12 | 37.5 | 20 | 62.5 | 0.961 |
| Serous carcinoma (n=24) | 11 | 45.8 | 13 | 54.2 | |
| Urinary bladder cancer (n=23) | 11 | 47.8 | 12 | 52.2 | NA |
| Lung | |||||
| Adenocarcinoma (n=49) | 38 | 77.6 | 11 | 22.3 | 0.034 |
| Bronchoalveolar carcinoma (n=5) | 1 | 20 | 4 | 80 | |
| Squamous cell carcinoma (n=18) | 14 | 77.8 | 4 | 22.2 | |
| Large cell carcinoma (n=8) | 7 | 87.5 | 1 | 12.5 | |
| SCLC (n=24) | 20 | 83.3 | 4 | 16.7 | |
| Ovarian | |||||
| Endometrioid cancer (n=27) | 20 | 74.1 | 7 | 25.9 | 0.180 |
| Serous cancer (n=27) | 21 | 77.8 | 6 | 22.2 | |
| Mucinous cancer (n=10) | 10 | 100 | 0 | 0 | |
| Breast | |||||
| Ductal carcinoma (n=11) | 9 | 81.8 | 2 | 18.2 | 0.815 |
| Mucinous carcinoma (n=7) | 7 | 100 | 0 | 0 | |
| Tubular carcinoma (n=3) | 3 | 100 | 0 | 0 | |
| Medullary carcinoma (n=31) | 28 | 90.3 | 3 | 9.7 | |
| Lobular carcinoma (n=6) | 5 | 83.3 | 1 | 16.7 | |
| Parotid gland | |||||
| Pleomorphic adenoma (n=14) | 6 | 42.9 | 8 | 57.1 | 0.001 |
| Adenolymphoma (n=17) | 4 | 23.5 | 13 | 76.5 | |
| Cylindroma (n=11) | 10 | 90.9 | 1 | 9.1 | |
| Well-differentiated NET (n=23) | 19 | 82.6 | 4 | 17.4 | NA |
| Thymoma (n=9) | 8 | 88.9 | 1 | 10.1 | NA |
| Total (n=713) | 526 | 73.8 | 187 | 26.2 | |
NA, Not applicable.