Characteristics of patients with retinoblastoma
| Variables | Number of patients | |
|---|---|---|
| n (Total=79) | Per cent | |
| Age at diagnosis (months) | ||
| Median (range) | 22.2 | (1–99) |
| Age at operation (months) | ||
| Median (range) | 25.9 | (1–113) |
| Male sex | 44 | 55.7 |
| Family history of RB | 2 | 2.5 |
| Multifocal tumours | 6 | 7.6 |
| Bilateral tumours | 18 | 22.8 |
| International RB stage | ||
| Stage I | 73 | 92.4 |
| Stage II | 0 | 0.0 |
| Stage III | 0 | 0.0 |
| Stage IV | 6 | 7.6 |
| Pathological tumour stage | ||
| pT1 | 35 | 44.3 |
| pT2 (a:b) | 23 (11:0) | 29.1 |
| pT3 (a:b) | 17 (11:6) | 21.5 |
| pT4 (a:b) | 3 (1:2) | 3.8 |
| Unclassifiable | 1 | 1.3 |
| Optic nerve invasion | 32 | 41.0 |
| Choroidal invasion | 24 | 30.8 |
| Extraocular invasion | 12 | 15.2 |
| Nodal or distant metastasis | 6 | 7.6 |
| Histopathological features | ||
| Necrosis | 62 | 78.5 |
| Calcification | 59 | 78.7 |
| Differentiation | 45 | 63.4 |
| Further treatment | ||
| Preop. chemoradiotherapy | 19 | 24.1 |
| Preop. local/proton therapy | 10 | 12.7 |
| Postop. chemoradiotherapy | 21 | 26.6 |
Postop, postoperative; Preop, preoperative; RB, retinoblastoma.