Table 1

The percentage of mutations found at each mutation hotspot shown for the labs in Leeds and Cardiff

AssayLeeds (% mutations)Cardiff (% mutations)
KRAS codons 12/1332/97 (33)31*/94 (33)
KRAS codon 613/96 (3.1)3/95 (3.2)
KRAS codon 1461/95 (1.1)1/92 (1.1)
BRAF codon 60012/96 (12.5)12/94 (12.8)
NRAS codons 12/132/95 (2.1)2/93 (2.1)
NRAS codon 612/95 (2.1)2/95 (2.1)
PIK3CA codons 542–54610/95 (10.5)9/94 (9.6)
PIK3CA codon 10471/96 (1.0)2/93 (2.1)
  • The percentages reflect the number of samples which yielded a result.

  • *The discrepancy in mutation detection at KRAS codons 12/13 is due to the fact that one of the samples which failed testing in Cardiff was found to have a mutation when tested successfully in Leeds.