Correlation with SRPK1 score | Multivariate logistical regression | ||||
---|---|---|---|---|---|
Variable | Spearman's rank correlation coefficient | p Value | OR | 95% CI | p Value |
Age at surgery (years) | −0.02 | 0.77 | 1.10 | 0.98 to 1.23 | 0.100 |
Preoperative PSA (ng/mL) | −0.15 | 0.12 | 0.97 | 0.86 to 1.10 | 0.664 |
Gleason grade | 0.12 | 0.21 | 3.47 | 1.23 to 9.81 | 0.019 |
T-stage | 0.27 | 0.004 | 2.24 | 0.58 to 8.60 | 0.239 |
Extracapsular perineural invasion | 0.25 | 0.008 | 0.89 | 0.15 to 5.31 | 0.902 |
Extracapsular extension | 0.28 | 0.003 | 1.07 | 0.11 to 10.2 | 0.955 |
Positive surgical margins | 0.08 | 0.41 | 2.28 | 0.67 to 7.75 | 0.187 |
Biochemical recurrence | 0.08 | 0.41 | NA | NA | NA |
SRPK1 expression* | NA | NA | 0.92 | 0.30 to 2.80 | 0.885 |
*SRPK1 expression converted to a dichotomous variable for purposes of multivariate logistical regression; high (expression score 3) and low (expression scores 0, 1 and 2).
NA, not applicable; PSA, prostate-specific antigen; SRPK1, serine-arginine protein kinase 1.