Table 5

Correlation of increased paxillin gene copy number with chromosome 12 and paxillin expression in lung adenocarcinoma with BAC component

Case	Histological component	Paxillin	p Value	α-12	p Value	Paxillin expression^*
Reference	Normal	2.04		1.85
1	BAC	2.50	<0.0001	2.03	0.035
	INV	2.64	<0.0001	1.85	1	Weak
2	BAC	2.70	<0.0001	2.07	0.014	Moderate
3	INV	3.87	<0.0001	3.37	<0.0001	None
4	BAC	2.97	<0.0001	2.48	<0.0001
	INV	4.30	<0.0001	0.05	<0.0001	Weak
5	BAC	3.92	<0.0001	2.92	<0.0001
	INV	3.64	<0.0001	2.67	<0.0001	Weak
6	BAC	2.96	<0.0001	2.00	0.025
	INV	2.35	0.011	2.04	0.035	Moderate
7	INV	2.59	<0.0001	2.11	0.0037	NA
8	INV	2.40	<0.0001	1.95	0.16	High
9	BAC	2.63	<0.0001	1.79	0.51
	INV	2.65	<0.0001	2.00	0.12	Moderate
10	INV	2.97	<0.0001	2.68	<0.0001
	LN	4.33	<0.0001	3.17	<0.0001	Weak
11	BAC	4.58	<0.0001	2.67	<0.0001	High
12	BAC	4.24	<0.0001	3.81	<0.0001
	INV	5.48	<0.0001	4.59	<0.0001	None
13	INV	3.21	<0.0001	2.95	<0.0001
	LN	3.19	<0.0001	2.67	<0.0001	None

The average number of fluorescent signals per nuclei are given for paxillin and chromosome 12 (α-12).
↵* See the Methods section for description of expression levels.
BAC, bronchioloalveolar carcinoma; INV, non-BAC component; NA, immunohistochemistry for case 7 was not interpreted because of technical difficulties.