TableĀ 5

Mismatch repair (MMR) discrepant cases between the two laboratories

MMR markerDiscrepant case(s)Leeds resultCardiff resultConsensus result
MLH1V007PositiveNegativePositive
MSH2V007PositiveNegativePositive
MSH6V007PositiveNegativePositive
PMS2V007PositiveNegativePositive
PMS2V442NegativePositiveNegative
  • Discrepant cases were so labelled, where a result of the whole section staining for a particular case was generated in both laboratories, but these results differed. One sample (V007) was discrepant for all four proteins, and one other case (V442) gave a discrepant result for PMS2 only.