Table 12

Clinical studies of lactobacilli showing efficacy for treatment of periodontal disease

BacteriaDosePathologyRef. (Design)
L. salivarius WB21
+
Xylitol
6.7×108 CFU

280 mg
Severe periodontitis treatment274(randomised clinical study)
L. reuteri ATCC 55730,
L. reuteri ATCC PTA 5289
1×108 CFU/gum (of each)Gingival inflammation275(double-blind placebo-controlled study)