Comparison of the molecular and immunohistochemical markers with pathological characteristics (n=174)
| Variable | Categorisation | Cx43 expression | ||
|---|---|---|---|---|
| Score 0 or 1+ | Score 2+ | p Value | ||
| Tumour stage48† | ||||
| pTa | 76 (84) | 14 (16) | 0.815 | |
| pT1 | 54 (79) | 14 (21) | ||
| pT2 | 10 (77) | 3 (23) | ||
| pT3 | 2 (100) | 0 (0) | ||
| pT4 | 1 (100) | 0 (0) | ||
| Histological grade48† | ||||
| G1 | 40 (91) | 4 (9) | 0.195 | |
| G2 | 68 (78) | 19 (22) | ||
| G3 | 35 (81) | 8 (19) | ||
| Histological grade49‡ | ||||
| Low grade | 89 (88) | 12 (12) | 0.026 | |
| High grade | 54 (74) | 19 (26) | ||
| Adjacent carcinoma in situ‡ | ||||
| No | 128 (81) | 30 (19) | 0.311 | |
| Yes | 15 (94) | 1 (6) | ||
| Multiplicity‡ | ||||
| Solitary | 109 (88) | 15 (12) | 0.004 | |
| Multifocal | 34 (68) | 16 (32) | ||
| Growth pattern‡ | ||||
| Papillary | 130 (82) | 29 (18) | 1.000 | |
| Solid | 13 (87) | 2 (13) | ||
| Immunohistochemistry | ||||
| Ki-67 labelling index | ||||
| ≤10% | 95 (88) | 13 (12) | 0.014 | |
| >10% | 48 (73) | 18 (27) | ||
Data are presented as numbers (percent).
†χ2 Pearson (two-sided); bold face representing p values <0.05.
‡Fisher’s exact test (two-sided); bold face representing p values <0.05.