The percentages of laboratories either meeting the UK guidelines for extended RAS testing, or indeed overtesting or undertesting
| Run 1 (n=99) | Run 2 (n=108) | |
|---|---|---|
| Percentage of laboratories exactly following UK guidelines | 6.1 | 25.9 |
| Percentage of laboratories overtesting | 19.2 | 10.2 |
| Percentage of laboratories undertesting | 68.7 | 55.6 |
| Percentage of laboratories where the testing panel was undetermined | 6 | 8.3 |
| TOTAL percentage of laboratories testing at least in accordance with UK guidelines | 25.3 | 36.1 |
Adding together the laboratories following the UK guidelines and those overtesting gives the total percentage of laboratories meeting or exceeding the minimum requirements. The UK guidelines suggest the following coverage: KRAS codons 12, 13, 59, 61, 117 and 146 in addition to NRAS codons 12, 13, 59 and 61.