TableĀ 2

Categorisation of MBCs based on PD-L1 expression in tumour cells and low or high PD-1 expression in TILs

TypeTumour microenvironment
(PD-L1/PD-1 TILs)
Number of cases
1PD-L1 positive, high PD-1*16 (23%)
2PD-L1 negative, low PD-1*22 (31%)
3PD-L1 positive, low PD-1*14 (20%)
4PD-L1 negative, high PD-1*19 (26%)
  • *PD-1 categorisation as high or low is done around the median of 22.5.

  • MBC, metaplastic breast carcinoma; PD-1, programmed cell death 1; PD-L1; programmed death-ligand 1; TIL, tumour infiltrating lymphocyte.