General characteristics and subgroup analysis of the patients with (n=19) and without (n=108) granulomatous inflammation on the specimen of resected lung
| Total | Only cancer | Coexisting granulomatous inflammation with lung cancer | p Value | |
|---|---|---|---|---|
| Number | 127 | 108 | 19 | |
| Age | 68 (26–89) | 69 (26–89) | 63 (40–84) | 0.06 |
| Gender—males | 74 (58.2%) | 62 (57.4) | 12 (63.1) | 0.78 |
| Location of lesion | ||||
| Right upper lobe | 35 (27.5) | 28 (25.9) | 7 (36.8) | 0.40 |
| Right middle lobe | 13 (10.2) | 11 (10.1) | 2 (10.5) | 1.0 |
| Right lower lobe | 19 (14.9) | 17 (15.7) | 2 (10.5) | 0.73 |
| Left upper lobe | 23 (18.1) | 21 (19.4) | 2 (10.5) | 0.52 |
| Lingula | 2 (1.5) | 2 (1.8) | 0 | 1.0 |
| Left lower lobe | 20 (15.7) | 15 (13.8) | 5 (26.3) | 0.18 |
| Bilateral | 5 (3.9) | 3 (2.7) | 2 (10.5) | 0.16 |
| Type of surgery | ||||
| Wedge resection | 44 (34.6) | 36 (33.3) | 8 (42.1) | 0.42 |
| Lobectomy | 45 (35.4) | 36 (33.3) | 8 (42.1) | 0.42 |
| Others | 1 (0.07) | 36 (33.3) | 2 (10.5) | 0.16 |
| Histology type | ||||
| Adenocarcinoma | 82 (64.5) | 71 (66) | 11 (57.8) | 0.60 |
| Squamous cell carcinoma | 12 (9.4) | 10 (9) | – | 0.35 |
| Large-cell carcinoma | 2 (1.5) | 1 (1) | 1 (5.2) | 0.27 |
| Others | 27 (21.2) | 23 (21) | 4 (21) | 1.0 |
| Died | 18 (14.1) | 15 (14) | 3 (16) | 0.73 |
| History of tuberculosis | 4 (3.1) | 2 (1.8) | 2 (11) | 0.10 |
| History of non-tuberculous mycobacteria | 3 (2.3) | 1 (0.09) | 2 (11) | 0.05 |
| Chemotherapy | 30 (23.6) | 23 (21.2) | 7 (36.8) | 0.15 |
| Survival, median (range)—days | 451 (22–2452) | 449 (29–2452) | 478 (22–1569) | 0.56 |
| 1-year survival | 68 (53.5) | 58 (54) | 10 (53) | 1.0 |
| 2-year survival | 27 (21.2) | 20 (19) | 7 (37) | 0.12 |
| 3-year survival | 11 (8.6) | 7 (6) | 4 (21) | 0.06 |
| Tuberculosis treatment | 1 (0.07) | 0 | 1 (5.2) | 0.14 |
| Stage | ||||
| I and II | 97 (76.3) | 84 (77.7) | 13 (68.4) | 0.38 |
| IIIA | 30 (23.6) | 24 (22.2) | 6 (31.5) | 0.38 |
| Granulomatous inflammation in parenchyma | 19 (14.9) | – | 19 (100) | – |
| Granulomatous inflammation in parenchyma and lymph nodes | 5 (3.9) | – | 5 (26.3) | – |
Data presented as number (%) or median (range).