Table 3

Mutation concordance analysis for the Idylla NRAS-BRAF mutation test for NRAS compared with MassARRAY. Table entries on the diagonal with orange shading are concordant results. The one discordant result, G12D with Idylla and WT with MassARRAY, is shaded light blue and discussed in the text

IdyllaMassARRAY
G12AG12VG12CG12DG12SG13DQ61HQ61KQ61LG61RA146T/VWT
G12A/V140000000000
G12C002000000000
G12D0001100000001*
G12S000000000000
G13D000001000000
Q61H000000100000
Q61K000000070000
Q61L000000003000
G61R000000000600
A146T/V000000000000
WT0000000000205
  • The orange entries on the diagonal highlight the correspondence between the MassARRAY and Idylla results. The one discrepant result has a light blue background.

  • *ddPCR confirmed the G12D result (<5%‚ÄČallelic frequency).

  • WT, wild type.