Regular ArticleA High Prevalence of HLA-H 845A Mutations in Hemochromatosis Patients and the Normal Population in Eastern England☆
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Cited by (58)
Iron Metabolism and Related Disorders
2013, Emery and Rimoin's Principles and Practice of Medical GeneticsHemochromatosis Genotypes and Risk of Iron Overload-A Meta-Analysis
2011, Annals of EpidemiologyCitation Excerpt :The studies varied in their geographical setting, with 79.1% being of European origin (8, 19–21, 24–38, 41–45, 47–50, 52–55). One study was prospective (25), 33 studies were case-control studies (8, 20, 26–34, 35–55), seven studies were cross-sectional (18, 19, 23, 24), and two studies had combined design, cross-sectional, and case-control (21, 22). Homozygosity for the C282Y mutation conferred the highest risk for both provisional and documented iron overload (Figure 2 and Supplementary Table 2) and accounted for the majority of iron overload cases in all studies (37.2%) (Supplementary Table 1).
EASL clinical practice guidelines for HFE hemochromatosis
2010, Journal of HepatologyA European allele map of the C282Y mutation of hemochromatosis: Celtic versus Viking origin of the mutation?
2003, Blood Cells, Molecules, and DiseasesGenetics and quaternary prevention. The example of haemochromatosis
2003, Atencion PrimariaThe evolutionary adaptation of the C282Y mutation to culture and climate during the European Neolithic
2016, American Journal of Physical Anthropology
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