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Isolation and structure of bombesin and alytesin, two analogous active peptides from the skin of the european amphibiansBombina andAlytes

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  • Pharmacologica
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Riassunto

Viene descritto l'isolamento e il chiarimento della struttura della bombesina e della alytesina due tetradecapeptidi attivi a struttura analoga presenti nella pelle fresca rispettivamente dellaBombina e dell'Alytes, anfibi europei della famiglia dei discoglossidi. I due polipeptidi manifestano azioni farmacologiche similari sulla pressione del sangue, su svariati organi a muscoli lisci, sulla secrezione gastrica e sulla glicemia.

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References

  1. V. Erspamer, G. Falconieri Erspamer andM. Inselvini, J. Pharm. Pharmac., in press.

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Authors and Affiliations

  1. Istituto di Ricerca di Base, Farmitalia S.p.A., Milano e Istituto di Farmacologia medica, Università di Roma, Italy

    A. Anastasi, V. Erspamer & M. Bucci

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  1. A. Anastasi
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  2. V. Erspamer
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  3. M. Bucci
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In part supported by grants from the Consiglio Nazionale delle Ricerche, Rome.

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Anastasi, A., Erspamer, V. & Bucci, M. Isolation and structure of bombesin and alytesin, two analogous active peptides from the skin of the european amphibiansBombina andAlytes. Experientia 27, 166–167 (1971). https://doi.org/10.1007/BF02145873

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  • DOI: https://doi.org/10.1007/BF02145873

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