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A primary retroperitoneal serous cystadenocarcinoma with clinically aggressive behavior

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Abstract

Case report

We describe a 44-year-old woman with a primary retroperitoneal serous cystadenocarcinoma as the fourth report in the world literature. A contrast-enhanced computed tomographic scan of the abdomen demonstrated a mass with enhanced solid mural nodules and septa in the left retroperitoneum. Serum CA19–9 was elevated at 181 U/ml. The patient underwent a complete resection of the retroperitoneal tumor with a partial resection of the psoas major muscle and its fascia. Pathological examination showed a well-differentiated papillary serous cystadenocarcinoma of ovarian type and locoregional lymph node metastases. Seven months after surgery, the patient developed a pelvic recurrence, and underwent a total hysterectomy, a left salpingo-oophorectomy and a resection of the metastatic mesenteric mass. Two months after the second surgery, serum CA19–9 and CA125 increased to 1,114 U/ml and 218 U/ml, respectively. A solitary liver metastasis was confirmed on a computed tomographic scan. The patient is now being treated with weekly docetaxel and carboplatin.

Conclusion

The present case illustrates the clinically aggressive nature of a primary retroperitoneal serous cystadenocarcinoma.

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Authors and Affiliations

  1. Department of Internal Medicine, Kaku Clinic, Kobe, Japan

    M. Kaku

  2. Department of Obstetrics and Gynecology, Kohnan Hospital, 5–16, 1-Chome Kamokogahara Higashinada-Ku, 658–0064, Kobe City, Hyogo Prefecture, Japan

    N. Ohara

  3. Department of Surgery, Rokko Island Hospital, Kobe, Japan

    Y. Seima & K. Imanishi

  4. Department of Obstetrics and Gynecology, Tomura Ladies Clinic, Kobe, Japan

    N. Tomura

  5. Department of Obstetrics and Gynecology, Kobe Kaisei Hospital, Kobe, Japan

    A. Kobayashi

  6. Department of Obstetrics and Gynecology, Kanebo Memorial Hospital, Kobe, Japan

    M. Yamasaki

  7. Department of Radiology, Kohnan Hospital, 5–16, 1-Chome Kamokogahara Higashinada-Ku, 658–0064, Kobe City, Hyogo Prefecture, Japan

    Y. Hirata

  8. Department of Pathology, Kohnan Hospital, 5–16, 1-Chome Kamokogahara Higashinada-Ku, 658–0064, Kobe City, Hyogo Prefecture, Japan

    S. Murao

Authors
  1. M. Kaku
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  2. N. Ohara
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  3. Y. Seima
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  4. K. Imanishi
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  5. N. Tomura
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  6. A. Kobayashi
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  7. M. Yamasaki
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  8. Y. Hirata
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  9. S. Murao
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Corresponding author

Correspondence to N. Ohara.

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Kaku, M., Ohara, N., Seima, Y. et al. A primary retroperitoneal serous cystadenocarcinoma with clinically aggressive behavior. Arch Gynecol Obstet 270, 302–306 (2004). https://doi.org/10.1007/s00404-003-0550-5

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  • DOI: https://doi.org/10.1007/s00404-003-0550-5

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