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Basaloid cell carcinoma of the prostate. Case report and review of the literature

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Abstract

We report on a case of malignant basal cell carcinoma of the prostate combined with a poorly differentiated conventional adenocarcinoma, infiltrating bilaterally the seminal vesicles and with lymph-node and distant metastases. Basal cell carcinoma represented the prevalent component of the tumour (80%), showed high mitotic activity, extensive perineural infiltration and vascular invasion and was immunoreactive for basal cell related antigens (high molecular weight cytokeratins 34βE12 and p63). Our data confirm previous observations that basal cell carcinoma represents an aggressive tumour with an adverse clinical outcome.

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Authors and Affiliations

  1. Division of Pathology and Laboratory Medicine, European Institute of Oncology, Via Ripamonti 435, 20141 , Milan, Italy

    Mauro G. Mastropasqua, Giancarlo Pruneri, Giuseppe Renne & Giuseppe Viale

  2. School of Medicine, University of Milan, Milan, Italy

    Mauro G. Mastropasqua, Giancarlo Pruneri, Giuseppe Renne & Giuseppe Viale

  3. Division of Urology, European Institute of Oncology, Milan, Italy

    Ottavio De Cobelli

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  1. Mauro G. Mastropasqua
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  2. Giancarlo Pruneri
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  3. Giuseppe Renne
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  4. Ottavio De Cobelli
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  5. Giuseppe Viale
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Correspondence to Giuseppe Viale.

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Mastropasqua, M.G., Pruneri, G., Renne, G. et al. Basaloid cell carcinoma of the prostate. Case report and review of the literature. Virchows Arch 443, 787–791 (2003). https://doi.org/10.1007/s00428-003-0911-2

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  • DOI: https://doi.org/10.1007/s00428-003-0911-2

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