Original contributionImmunophenotypic evaluation of the Bone Marrow in non-Hodgkin's lymphoma☆
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2021, Blood ReviewsCitation Excerpt :The latter is particularly seen when BMI is paratrabecular, which is most common in FL [19,28,36,40–42]. Conversely, sampling-related false negatives in DLBCL and other large cell lymphomas may be more likely secondary to their greater cellular fragility and tissue necrosis [17,43–45], as these have been reported as common sources of false negatives in lymph node samples [46–48]. Lack of observer experience or proficiency can also lead to false negative results of FC assessment of BMI, and a number of potential pitfalls should be borne in mind, even when an optimal antibody tube or panel is used.
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Presented in part at the 72nd Annual Meeting of the US and Canadian Academy of Pathology, Chicago, IL, March 1991.
Copyright © 1993 Published by Elsevier Inc.