Review
Cell cycle control in eukaryotes: molecular mechanisms of cdc2 activation

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Abstract

cdc2 kinase regulates the progression of eukaryotic cells through the division cycle. Events such as cell growth, DNA replication and mitosis are coordinated through the activation of specific forms of this kinase. Here I discuss our present knowledge of the mechanisms that regulate the activity of cdc2 kinase.

References (46)

  • P. Nurse et al.

    Mol. Gen. Genet.

    (1976)
  • P. Nurse et al.

    Genetics

    (1980)
  • D. Beach et al.

    Nature

    (1982)
  • L.M. Hereford et al.

    J. Mol. Biol.

    (1974)
  • R. Booher et al.

    Mol. Cell. Biol.

    (1986)
  • P. Nurse et al.

    Nature

    (1981)
  • J. Piggott et al.

    Nature

    (1982)
  • A. Lorincz et al.

    Nature

    (1984)
  • J. Hindley et al.

    Gene

    (1984)
  • S. Reed et al.
  • V. Simanis et al.

    Cell

    (1986)
  • M. Lee et al.

    Nature

    (1987)
  • G. Draetta et al.

    Cell

    (1987)
  • A. Murray et al.

    Science

    (1989)
  • M.J. Zoller et al.

    J. Biol. Chem.

    (1981)
  • K. Gould et al.

    Nature

    (1989)
  • A.M. Carr et al.

    Mol. Gen. Genet.

    (1989)
  • J. Hayles et al.

    Mol. Gen. Genet.

    (1986)
  • R. Booher et al.

    Cell

    (1989)
  • S. Moreno et al.

    Cell

    (1989)
  • T.A. Langan et al.

    Cell

    (1989)
  • T.A. Langan et al.
  • B. Lewin

    Cell

    (1990)

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