Cell
Volume 109, Issue 2, Supplement 1, 19 April 2002, Pages S109-S120
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Review
Transcription: Tantalizing Times for T Cells

https://doi.org/10.1016/S0092-8674(02)00705-5Get rights and content
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Abstract

The T helper lymphocyte is responsible for orchestrating an appropriate immune response to pathogens. To do so, it has evolved into two specialized subsets that direct type 1 and type 2 immunity. Here, we discuss the genetic programs that control lineage commitment of progenitor T helper cells along each of these pathways.

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