Journal of the American Academy of Dermatology
Tumors arising in nevus sebaceus: A study of 596 cases☆,☆☆
Section snippets
MATERIAL AND METHODS
All cases of NS diagnosed in the Laboratoire d’Histopathologie Cutanée of Strasbourg, France from 1932 through 1998 were included in this study. For this purpose, we reviewed all slides with any of the following diagnoses: nevus sebaceus, trichoblastoma, BCC, trichilemmoma, syringocystadenoma papilliferum (SCAP), tumor of the follicular infundibulum, sebaceous adenoma, and adnexal carcinoma. All slides were reviewed, and only typical cases of NS were included. The demographic data and the
Tumors associated with NS
Clinical data are presented in Table I.
Gender Empty Cell Female 290 (48.7%) Male 306 (51.3%) Age (y) at surgery ≤10 82 (13.7%) 11-16 150 (25.2%) 17-40 256 (43.0%) >40 94 (15.8%) Unknown 14 (2.3%) Locations Scalp 287 (48.1%) Face 233 (39.1%) Neck 35 (5.9%) Trunk 21 (3.5%) Unknown 20 (3.4%)
DISCUSSION
We analyzed 596 NS surgically excised at various ages and showed that more than 90% of tumors occurring in association with NS are actually benign. There were only 5 cases of true BCC (0.8%) and no other malignant tumors. Benign tumors were found in fewer than 2% of NS excised in children.
The two most common tumors were SCAP and trichoblastoma. These findings are well correlated with those of Chun, Vazquez, and Sanchez.7 In all other large series in which trichoblastomas were not discussed,
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Reprint requests: B. Cribier, Clinique Dermatologique, CHU, 1 place de l’Hôpital 67091 Strasbourg, France.
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