Regular ArticleParathyroid carcinoma: problems in diagnosis and the need for radical surgery even in recurrent disease
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Cited by (41)
Local resection versus radical surgery for parathyroid carcinoma: A National Cancer Database analysis
2021, European Journal of Surgical OncologyCitation Excerpt :Parathyroid carcinoma (PC) is a rare malignancy, and its low incidence has resulted in a dearth of evidence-based guidelines for management [1–3]. In addition, it is difficult to diagnose preoperatively in the absence of overt symptoms [4–8]. This presents a unique clinical quagmire for surgeons when final histopathology reveals carcinoma after parathyroidectomy for a presumed benign indication.
Non-functional water clear cell parathyroid carcinoma masquerading as medullary thyroid carcinoma
2021, Annals of Diagnostic PathologyCitation Excerpt :Atypical mitoses are a more specific indicator of malignancy [1,12]. Perineural invasion has also been recognized as a feature of malignancy, although it was not a common feature in the reported cases [11,13]. Parathyromatosis is a condition caused by seeding of the surgical field by parathyroid tissue during surgical removal in benign conditions; the parathyroid tissue grows in an infiltrative pattern, mimicking parathyroid carcinoma.
Parathyroid carcinoma
2010, Otolaryngologic Clinics of North AmericaCitation Excerpt :The frequency of parathyroid carcinoma is reported as greater than 1% of patients with primary hyperparathyroidism,10,11 although a higher rate of 5% is reported from Japan.4,12 It is the least common endocrine malignancy,10,13–16 with a prevalence of 0.005%17 of all cancers. According to a report from the National Cancer Data Base, the estimated incidence is 30 new cases per year in the United States.17
Parathyroid carcinoma in a child: an unusual case of an ectopically located malignant parathyroid gland with tumor invading the thymus
2009, Journal of Pediatric SurgeryCitation Excerpt :Although few parathyroid carcinomas will be found to infiltrate the surrounding structures at the time of operation unless well advanced, the surgeon must rely on clinical intuition and intraoperative surgical pathologic condition to make the diagnosis of malignancy. As with other endocrine abnormalities, the histologic distinction between benign and malignant tissue is often difficult [10]. A standard criterion for pathologic diagnosis was established in 1973 after analysis of 70 patients with parathyroid carcinoma.
Parathyroid carcinomas
2008, Endocrinologia y NutricionParathyroid carcinoma: Imaging features of initial presentation and recurrence. A single center experience
2024, Neuroradiology Journal
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Correspondence to: Priv. Doz. Dr. C. Dotzenrath, St. Antonius Kliniken, II. Chirurgische Klinik, 42107 Wuppertal, Hardtstr. 46, Germany. Tel: +49 02022994410; Fax: +49 02022994415; E-mail: [email protected]