Regular ArticleHepatitis viral status affects the pattern of intrahepatic recurrence after resection for hepatocellular carcinoma
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Risk factors associated with early and late recurrence after curative resection of hepatocellular carcinoma: A single institution's experience with 398 consecutive patients
2014, Hepatobiliary and Pancreatic Diseases InternationalAppropriate liver resection type for patients with the American joint committee on cancer classification T1 and T2 hepatocellular carcinoma
2011, European Journal of Surgical OncologyCitation Excerpt :Previous observations21 suggest the possible mechanisms responsible for postresectional intrahepatic recurrence in HCC, such as intrahepatic metastases from the primary tumor and multicentric carcinogenesis in the remnant liver. Some reports21–23 have suggested that early recurrence (within 2 years after resection) can be attributed to both intrahepatic recurrence from the primary tumor and the multicentric lesions, whereas late recurrence (more than 2 years) is predominantly of multicentric origin. Assuming that the incidence of multicentric origin is constant with time, our observation implies that major resection reduces the incidence of intrahepatic metastasis from the primary tumor.
Surgical management of hepatocellular carcinoma: Is the jury still out?
2009, Surgical OncologyCitation Excerpt :Sixteen of the papers included a multivariate analysis for overall and/or disease-free survival [20,22,24,26,27,29,33,34,37–41,45,46,48,49]. The results of these multivariate analyses were examined together with data obtained from numerous additional series which did not fit the inclusion criteria of the main analysis but in which a multivariate analysis was performed for survival [50–84]. A number of risk factors have been frequently reported as being of importance in predicting a poor outcome following resection and these can be summarised into: patient-related; tumour/liver-related and procedure-related.
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Correspondence to: Yoshio Shirai, MD, Division of Digestive and General Surgery, Niigata University Graduate School of Medical and Dental Sciences, 1-757 Asahimachi-dori, Niigata City, 951-8510 Japan. Business Tel: +81-25-227-2228; Business Fax: +81-25-227-0779; Home Tel: +81-25-222-1069; E-mail: [email protected]